Microbiology Procedure
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Index >> Virus Structure and Classification >> Structural Viral Proteins - (Nucleocapsid Proteins)

Structural Viral Proteins - (Nucleocapsid Proteins)

Structural Viral Proteins (Nucleocapsid Proteins)

The capsids of viruses are made up entirely of proteins.

The capsid proteins enclose the nucleic acid and protect it from nucleases in biologic fluids.

The capsid also promotes attachment to susceptible cells. The virus cannot have too many genes to specify different protein types. Hence it is made up of many identical protein units or protomers.

Helical capsids usually consist of a single protein type. Thus the TMV consists of a single RNA molecule coated by a single type of polypeptide. Icosahedral capsids may have one or several types of proteins. Adenoviruses contain at least 14 protein types.

The bacteriophage T4 contains some 30 different polypeptide chains.

The protomers are arranged in a definite architecture in toe capsid. This permits bonding between suitable chemical groups on their surfaces.

 

 

 

 

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