Microbiology Procedure
  Home  Link to us  Resources  Site map  Search  Language

Index >>Viruses and Cancer >>Transmission of Oncornaviruses

Transmission of Oncornaviruses

Transmission of Oncornaviruses - Transmission of the virus may be horizontal or vertical.
Horizontal transmission takes place from host to another by contagion, Vertical transmission takes place from parent to offspring.
Vertical transmission may be congenital or genetic.
Congenital transmission is from the mother to the offspring through the ovum, placenta or milk.
In the C3H strain of mice, milk, is ,the transmitter of the mouse mammary cancer agent.
Genetic transmission can take place through the father or the mother.
It is from one host generation to another as a DNA provirus.
Mammary tumours in the GR strain of mice are examples of genetic transmission.

Some viruses are transmitted only vertically. Such viruses are not very harmful to the host, because neither the host nor the virus would survive if they were.
Other viruses are typically transmitted horizontally, but may be incidentally transmitted vertically, e. g. rubella (German measles) may sometime, infect the human foetus congenitally.
Some viruses are horizontally transmitted in one host and vertically in another e. g. mosquito borne yellow fever virus and tick-borne encephalitis virus.
These viruses are pathogenic in the mammalian hosts (reservoirs) but usually harmless in the arthropod hosts (vectors).
The C type viruses are transmitted by all the three methods; horizontal, congenital and genetic.

 

Home | Site map | Submit Article | Resources | Search