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Main Index >> Viruses and Cancer

Viruses and Cancer
* Types of Cancer
* Characteristics of Cancer Cells
* Somatic Mutation Hypothesis
* Viral Gene Hypothesis
* Defective Immunity Hypothesis
* Other Theories for Viral and Chemical Carcinogensis
* DNA Viruses
* RNA Viruses
* Incorporation of Viral DNA in to the Genome of the Host
* List of Chemical Carcinogens
* Oncogenic Viruses - Papovaviruses
 

Viruses and Cancer


Viruses and Cancer - Cell division is a normal process in multicellular organisms. Growth and repair (replacement of dead cells) take place as a result of cell division (mitosis). Except for cells like the liver and brain cells, which rarely divide in the mature adult, most cells undergo frequent division. Sometimes, however, cell division becomes very rapid and uncontrolled, leading to cancer.

It should be clearly understood that rapid growth means a high rate of cell division for a particular cell type. It is possible for perfectly normal cells, e. g. the blood forming cells, to have a higher rate of division than some cancerous cells.

Cells which undergo rapid, abnormal and uncontrolled growth at the cost of remaining cells are called neoplastic cells. The growths resulting from the division of such cells are called neoplastic growth or tumour. Tumours are commonly classified as benign and, malignant. Abnormal and persistent cell division that remains localized at the spot of origin results in the so called benign tumours.

It should be noted, however, that benign tumours can sometimes be fatal, Ex. brain tumours that cause pressure on vital centres. benign tumours usually contain well differentiated cells. Tumour cells may be carried by the blood stream, or the lymphatic system, or by direct penetration to other parts of the body, where they may induce secondary(metastaiic) tumours.

Such invasive cancers ultimately result in the death of the organism and are therefore said to be, malignant. Malignant tumours usually contain undifferentiated cells, often with large nuclei and nucleoli.

 

* List of Some Papovaviruses
* Polyoma and SV 40 Viruses
* Replication of DNA
* Protein Synthesis
* Retroviruses
* Proteins of the Murine Leukemia Virus
* Oncornavirus Replicative Cycle
* Types of Tumor Virus Infection
* Abortive Infection
* Defective Infection
* Nonpermissive Infection
* Inactive Infection
* Defective and Helper Viruses
* Transmission of Oncornaviruses
 
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